Placebo more effective than antipsychotics for aggression in mental retardation Carlat Reports

Placebo more effective than antipsychotics for aggression in mental retardation

The Carlat Psychiatry Report, Volume 6, Number 2, February 2008
https://www.thecarlatreport.com/newsletter-issue/tcprv6n2/

From The Carlat Psychiatry Report, February 2008, Anticonvulsants in Psychiatry

Issue Links: Learning Objectives | Editorial Information

Topics: Antipsychotics

Max Fink, MD

In a multi-center study conducted in Great Britain and Australia, 86 adults with mental retardation (IQ < 75) and aggressive behavior were randomized to double-blind treatment with Risperdal (mean dose, 1.8 mg/day), Haldol (mean dose, 2.9 mg/day), or placebo. The primary outcome was score on the modified overt aggression scale (MOAS) at 4 weeks.

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Max Fink, MD

Professor of Psychiatry and Neurology Emeritus School of Medicine, SUNY Stony Brook

Disclosures: Dr. Fink has disclosed that he has no significant relationship or financial interests in any commercial companies pertaining to this educational activity.