Last April we reported on Pimavenserin – Nuplazid – the novel antipsychotic that’s FDA approved in psychosis related to parkinson’s disease. In that article we mentioned a randomized controlled trial from Mass General – the CLARITY trial - that showed...

We interview Ruta Nunacs on perimenopausal depression, and our word of the day – processomania – brings us into the crosshairs of politics and psychiatry. Published On: 10/18/20 Duration: 24 minutes, 42 seconds Article Referenced: "Mood and Menopause," The Carlat Psychiatry Podcast, October...

New labeling from the FDA requires physicians to discuss naloxone with patients or caregivers they are prescribing opioids to. The new guideline also recommends that we prescribe naloxone to anyone who is at risk for opioid overdose, even if we...

Benzo prescriptions have risen 34% during COVID-19, particularly in women. People are also getting benzos outside of prescriptions. Drs. Islam and Choudhry discussed the emerging trend in a commentary in Clinical Psychiatry News. Specifically, they are concerned that people will obtain...

Trintellix claims to improve cognition in depression, but what does this effect look like in patient’s lives? We speak with Tom Gualtieri about the cognitive side of antidepressants, and show you how to use a 3 minute cognitive test that...

A special edition for patients. Lithium is one of the most effective medications for bipolar and depression, but many of its marvels have remained obscure. Lithium has never benefited from a pharmaceutical ad (because it’s a mineral, not a medicine),...

When it comes to PTSD, pharmacotherapy is second-line and psychotherapy has the more robust evidence. The effect size for therapy is in the large range, while medications are in the small, with one exception…. In studies where patients are allowed...

How did the rate of depression triple over a single month in 2020? In this episode you’ll learn how to distinguish clinical depression from normal stress, so you’re better prepared to take care of the 1 in 3 U.S. adults...

In September 2020 the APA updated their schizophrenia practice guidelines. Here’s how things have changed since the 2004 edition. [Link] Date Published: 9/26/2020 Duration: 4 minutes, 27 seconds Transcript:  In September 2020 the APA updated their schizophrenia practice guidelines. Here’s...

When it comes to weight gain on antipsychotics, most of what we know is from industry sponsored trials, and most of them were done on Caucasian patients. Few of those studies compare the antipsychotics side by side, which leaves us...