SSRIs and Intracerebral Hemorrhage Risk

Topics: Bleeding | Citalopram | Depression | Escitalopram | Fluoxetine | Geriatric | Hemorrhagic | Intra-cerebral hemorrhage | Mortality | Paroxetine | Post-stroke depression | Prozac | Serotonin Specific Reuptake Inhibitors (SSRIs) | Sertraline | SSRIs | Stroke

REVIEW OF: Kubiszewski P et al, JAMA Neurol 2020;e203142. Epub ahead of print. Depression after strokes is very common, affecting about 50% of stroke patients. Many such patients are treated with SSRIs, which are generally effective but potentially dangerous because they can increase the risk of bleeding due to impaired platelet aggregation. This is

Can Antidepressants Prolong Survival in Cancer Patients?

Topics: Adherence | Cancer | Citalopram | Depression | Escitalopram | Fluoxetine | Mortality | Paroxetine | Prozac | Serotonin Specific Reuptake Inhibitors (SSRIs) | Sertraline | SSRIs

Review Of: Shoval G et al, Depress Anxiety 2019;36(10):921–929 Many cancer patients experience depression, especially those with poor prognoses. Compared with euthymic patients, depressed cancer patients are less adherent to their cytotoxic medications, and this poor adherence can worsen their long-term survival. Yet surprisingly, some studies have

Does Prozac Treat Repetitive and Stereotypical Behaviors in Children With Autism?

Topics: Autism | Autism Spectrum Disorder | Fluoxetine | Perseveration | Perseverative Behavior | Prozac | Repetitive Behavior | SSRIs | Stereotypical Behavior

Review of: Reddihough DS et al, JAMA 2019;322(16):1561–1569 Restrictive, repetitive, and stereotypical behaviors in children and adolescents with autism spectrum disorder (ASD) are a common concern, and there are no FDA-approved medications for their treatment. We know that fluoxetine is effective in the treatment of obsessive-compulsive disorder i

How to Come Off a Psych Med Part 1: Antipsychotics

Topics: Citalopram | Escitalopram | Fluoxetine | Prozac | Risk | Serotonin Specific Reuptake Inhibitors (SSRIs) | SSRIs | Violence

TCPR: There are a lot of books on deprescribing from the antipsychiatry movement, but your book seems to take a different approach.Dr. Gupta: The biggest difference is that the authors of this book all acknowledge that there is a place for psychotropic medications. They can be extremely beneficial for the patient in the right situation. My concern is wi

How to Select an SSRI

Topics: Antidepressants | Citalopram | Escitalopram | Fluoxetine | Prozac | Psychopharmacology | Psychotropic medication | Serotonin Specific Reuptake Inhibitors (SSRIs) | Sertraline | SSRIs

On March 14, 2012, Lexapro became the last SSRI to lose its patent, closing the book on a quarter century of science and marketing that changed and sometimes confused the way we think about antidepressants. Now that the unpublished studies have come to light and the incentives to favor one drug over another have dried up, it’s a good time to take a so

Mood and Menopause

Topics: Antidepressants | Citalopram | Depressive Disorder | Effexor | Escitalopram | Female Issues in Psychiatry | Fluoxetine | gabapentin | Gender | Hormone Replacement Therapy | Oral Contraceptives | Prozac | Serotonin Specific Reuptake Inhibitors (SSRIs) | SSRIs | Women’s Issues in Psychiatry

TCPR: When does perimenopausal depression tend to start?Dr. Nonacs: It’s during the transition into menopause that women are most vulnerable to depression. And that transition can actually take quite a while, like 5–7 years. TCPR: How does it present?Dr. Nonacs: Often they’ve had a history of depression, but have done fairly well up to this point