Agitation (October/November/December)

Date of Issue: 10/01/2021 | Volume: 1 | Number: 7&8

Issue Links:Learning Objectives

Dr. Metzger gives us tips for the management of agitation in patients with dementia and Dr Gray reviews the effects of anticholinergic medications on cognition. Also, we share guidelines for choosing medications to treat acute psychotic agitation.

In This Issue

Expert Q&A

Treating Agitation in Patients with Dementia

Topics: Agitation | Alzheimers | Antipsychotics | Benzodiazepines | BPSD (behavioral and psychological symptoms of dementia) | Dementia | Lewy Body Dementia | Parkinson’s Disease | Pharmacotherapy | Sundowning

The behavioral and psychological symptoms of dementia can be challenging to manage. Dr. Metzger discusses his approach in the diagnosis and treatment of agitated patients with dementia.

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Expert Q&A

Anticholinergic Drugs and Risk of Cognitive Impairment and Dementia

Topics: Alzheimers | Anticholinergic burden scale | Anticholinergics | Benzodiazepines | Cognitive Decline | Cognitive impairment | Dementia | Healthy aging | Pharmacotherapy

Might anticholinergic medications increase the risk of long-term cognitive impairment? Dr. Gray reviews the data.

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Clinical Update

Medications to Rapidly Treat Psychotic Agitation

Topics: Agitation | Antipsychotics | Aripiprazole | Benzodiazepines | Chlorpromazine | De-escalation | Diphenhydramine | Droperidol | Emergency | Haloperidol | Hydroxyzine | olanzapine | Pharmacotherapy | Promethazine | Psychosis | Quetiapine | Risperidone | Violence | Ziprasidone

How do you choose medications to calm an acutely psychotic and agitated patient? We'll tell you which ones are the safest and most effective.

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Research Update

Rapid-Onset Treatment for Pedophilic Disorder

Topics: Degarelix | Pedophilic Disorder | Prepubescent children | Sex offenders

Degarelix works quickly to reduce symptoms of pedophilic disorder, like sexual preoccupation.

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Research Update

Melatonin vs Memantine for ECT-Related Cognitive Impairment

Topics: Cognitive impairment | ECT | Melatonin | Memantine

Memantine appears more effective than melatonin in reducing post-ECT cognitive impairment.

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Research Update

Faster Refeeding of Patients With Anorexia Nervosa Appears Safe

Topics: Anorexia | Eating Disorders | Higher-calorie refeeding | Low calorie refeeding | Malnourishment | Refeeding syndrome

Higher calorie refeeding of patients with anorexia nervosa appears no less safe than low calorie refeeding and leads to quicker stabilization.

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Research Update

Can We Treat Depression by Targeting Inflammation?

Topics: Antibiotic | Depression | Inflammation | Minocycline | Mood | Pharmacotherapy

If inflammation plays a role in mood, it makes sense to explore the effects of antibiotics on depression. This study does just that.

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In Brief

IM Olanzapine Plus Benzodiazepines: Safe or Unsafe?

Topics: Antipsychotics | Benzodiazepines | olanzapine | Psychotic Agitation | Side Effects

If you have ever tried to electronically prescribe IM olanzapine with an IM/IV/subcutaneous benzodiazepine, you have probably received an interaction alert warning about the potential for excessive sedation and cardiorespiratory depression. Is this warning justified? Let’s look at the data.

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In Brief

Note From the Editor-in-Chief

Topics: Agitation | Anticholinergics | Cognitive functioning | Dementia | Geriatrics | Psychotherapy

Sometimes we have little choice but to administer sedating medications to a combative patient who is putting others at risk of injury. Which medications work most quickly, safely, and effectively?

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CME Post-Test

CME Post-Test - Agitation, CHPR, October-November-December 2021

Topics: CME Post-Test

The post-test for this issue is available for one year after the publication date to subscribers. By successfully completing the test you will be awarded a certificate for 2 CME credits.

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