A New Buprenorphine Dosing Strategy for Easier Induction From Fentanyl

Topics: Buprenorphine | fentanyl | induction | medication of opioid use disorder (MOUD) | Opioid Use Disorder

REVIEW OF: Antoine D et al, Am J Addict 2021;30(1):83–87 The escalating rate of opioid overdose deaths has been linked to the rise of illicit fentanyl. Increasing evidence shows that fentanyl and its analogues, such as carfentanil and acetylfentanyl, are fast replacing heroin as the most commonly used illicit opioid for many people with opioid use

Buprenorphine Induction Without Withdrawal

Topics: Buprenorphine | Buprenorphine Induction | medication of opioid use disorder (MOUD) | Opioid Use Disorder

REVIEW OF: Ahmed S et al, Am J Addict 2021;30(4):305–315 Buprenorphine is notorious for precipitating withdrawal in patients who have recently taken opioids. Its high receptor affinity and partial agonism at the mu receptor can make inductions tricky. Giving it too soon can cause severe withdrawal, yet giving it too late means patients are in disco