Topics: Antidepressants

In case you haven't noticed, antidepressants are under attack. Articles such as "The Emperor's New Drugs" and popular books like "Prozac Backlash" point to a growing public sentiment that psychiatrists need to shed a little hubris.

Throughout every issue of The Carlat Report, you, poor reader, have been subjected to citations of multiple research studies, and to terms such as "controlled," "open-label", "statistically significant." In this article, TCR dives head-first into research methodology, with the aim of helping you to become smarter consumers of statistical trickery.

Index to Volume 1, 2003 of The Carlat Report

Dr. Zimmerman, you and your colleagues have published prolifically on whether the research studies we read are truly relevant to our clinical practices. What's the bottom line of your research?