Topics: Antipsychotics | Anxiety | Bipolar Depression | Depression | Dosing | Psychopharmacology | Psychopharmacology Tips | PTSD | Quetiapine | Schizophrenia

It is the best of drugs; it is the worst of drugs. Quetiapine (Seroquel) has a few benefits that are unmatched by other medications, and here we explore where it fits in depression, bipolar, schizophrenia, as well as off-label uses like anxiety and sleep.

Topics: Antipsychotics | Depression | Psychosis

Psychotic depression is difficult to detect, and antipsychotics are not as effective in this condition as we’d like to think. Conrad Swartz explains why 1 in 3 cases of psychotic depression are missed, its complex relationship to trauma, and how to treat it.

Topics: Anxiety | Anxiety Disorder | Benzodiazepines | Hypnotics

Former Chairman of the American Psychiatric Association Benzodiazepine Task Force Carl Salzman explains the legitimate medical use of benzodiazepines and their relevance in psychiatric practice.

Topics: Anxiety | Citalopram | Depression | Escitalopram | SSRIs

Citalopram and escitalopram are very similar drugs, but there are reasons to prefer one over the other.

Topics: Depression | rTMS | TMS | Transcranial Magnetic Stimulation | Treatment-Resistant Depression

Most antidepressant therapies can induce mania, and this study looks at whether TMS belongs on that list. We report on the latest findings.

A landmark study puts a spotlight on whether patients can successfully taper off their antidepressant without relapsing.

Topics: Depression | Medical Comorbidities | Meta-analysis

An analysis of 348,014 patients suggests the hypothyroid-depression link is not as strong as once thought.

Topics: Metabolic syndrome | Schizophrenia | Special populations | Topiramate | Weight gain

This study looked at adjunctive topiramate for weight in a patient population inherently more vulnerable to cardiometabolic disturbance.