Antidepressant Roundup 2006 (January)

Date of Issue: 01/01/2006 | Volume: 4 | Number: 1

Issue Links:Learning Objectives | Editorial Information

Teaser to be posted soon.

In This Issue

Article

Vagus Nerve Stimulation: Is the Evidence Convincing?

Topics: Antidepressants | Brain Devices

Vagus nerve stimulation (VNS) is certainly new—but is it effective? It took the FDA a long time to make up its mind, but eventually it approved the treatment in May 2005. (For more details on why the FDA flip-flopped on the issue, see “FDA Approval of VNS,” this issue.) In this article, we scrutinize the two pivotal studies leading to approval.

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Article

FDA Approval of VNS: The All-Too-Human Side of a Bureaucracy

Topics: Antidepressants | Brain Devices

First they said yes to VNS, then no, then yes. And now they’re trying desperately to explain their final answer.

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Article

VNS: Some Practical Information

Topics: Antidepressants | Brain Devices | Practice Tools and Tips

If, after reviewing our admittedly lukewarm evaluation of the VNS data, you decide that you want to offer it to your patients, here’s some useful information.

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Expert QA

Choosing Antidepressants

Topics: Antidepressants

Most psychiatrists pretty much agree that all antidepressants are more or less equally effective. So if you start with that premise and you have 10-15 antidepressants out there, why are you picking one versus another? And what algorithm are we all using? Dr. Zimmerman developed a questionnaire for psychiatrists to fill out immediately after they wrote antidepressant prescriptions. We asked, “What influenced you to choose that medication?”

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