Antipsychotic Roundup 2007 (March)

Date of Issue: 03/01/2007 | Volume: 5 | Number: 3

Issue Links:Learning Objectives | Editorial Information

Teaser to be posted soon.

In This Issue

Article

Invega: Can You Say "Patent Extender?"

Topics: Antipsychotics

Janssen’s marketing team apparently missed the fact that the word in the English language that sounds most like “Invega” is “inveigle,” meaning “to entice, lure, or ensnare by flattery or artful talk or inducements” (www.dictionary.com). You may have already heard some “artful talk” from your Janssen reps, who are keen to have you convert your patients from Risperdal to Invega.

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Article

Do Second-Generation Antipsychotics Treat Depression? An Update

Topics: Antipsychotics

In this article, guest author Dr. Shalom Feinberg, takes a hard look at the most recent data on the effectiveness of SGAs for depression in its various guises, including treatment-resistant depression (TRD) and bipolar depression (BD).

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Expert QA

Choosing the Right Antipsychotic

Topics: Antipsychotics

Dr. Carpenter, as Editor-in-Chief of Schizophrenia Bulletin and a long-time researcher in the field, I’m sure you’ve seen trends come and go. Lately, we’ve been hearing a lot about how the older, conventional antipsychotics may be just as good as the newer atypicals. What’s your take?

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Research Update

College students love to abuse Adderall

Adderall has overtaken Ritalin as the most-abused stimulant among college students. In a survey, 4,580 college students were asked about their illicit use of drugs.

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Research Update

Bad News for Transcranial Magnetic Stimulation

Topics: Antidepressants

An FDA advisory panel has recommended that TMS not be approved for the treatment of major depression. Neuronetics, the maker of the NeuroStar device (www.neuronetics.com), submitted data from three studies, but only one was a placebo-controlled double-blind trial (Study 101).

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Research Update

Seroquel vs. Depakote for Impulsivity and Aggression in Teens

Topics: Antipsychotics | Mood Stabilizers

We often see teenagers with co-occurring bipolar disorder and aggressive/impulsive behaviors. While Depakote is often effective, we also often prescribe atypical antipsychotics. A new post-hoc analysis provides some evidence to bolster that practice.

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Research Update

Omega-3 Fatty Acids for Suicidal Behavior

Topics: Natural Medications

Omega-3 fatty acids have been studied in a number of psychiatric disorders, including autism, bipolar disorder, depression, and schizophrenia. A new study shows a possible benefit for patients with a history of self-harm.

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Research Update

Metformin for Antipsychotic-Induced Weight Gain in Adolescents

Topics: Antipsychotics

Atypical antipsychotics can cause significant weight gain in adolescents. In this study, 39 kids between 10 and 18 years of age were randomized to receive either the antidiabetic drug Glucophage (metformin) or a matched placebo; each was added to their primary antipsychotic medication (Risperdal, Seroquel, or Zyprexa) for 16 weeks.

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