Treating Personality Disorders (September)

Date of Issue: 09/01/2008 | Volume: 6 | Number: 9

Issue Links:Learning Objectives | Editorial Information

Teaser to be posted soon.

In This Issue

Article

Topics in Personality Disorders

Topics: Personality Disorders

Are you diagnosing a personality disorder (PD) in half of your patients? If not, you probably are not asking enough questions.

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Article

Medications for Borderline Personality Disorder

Topics: Personality Disorders

Most authorities in the world of borderline personality disorder (BPD) say that psychotherapy is the mainstay of treatment and that medications should only be used adjunctively to treat symptoms as they arise. Nevertheless, medications are used relatively frequently for this disorder.

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Expert QA

Diagnosing Personality Disorders

Topics: Personality Disorders

This split between Axis I and II came about in 1980 with the publication of DSM-III. It came out of a concern that disorders like personality disorders, learning disorders, mental retardation and autism could be overlooked because other, more florid disorders would take everyone’s attention.

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Research Update

Gabitril fails to improve GAD symptoms in three controlled trials

Topics: Anxiety Disorder

Cephalon’s selective GABA reuptake inhibitor, the antiepileptic drug tiagabine (Gabitril), was assessed for the treatment of generalized anxiety disorder in adults in three large 10-week placebo-controlled studies.

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Research Update

Vanda’s antipsychotic candidate iloperidone rejected by FDA

Topics: Antipsychotics

The FDA issued a Not Approvable letter regarding Vanda Pharmaceutical’s antipsychotic medication iloperidone (Fanapta). The agency based its decision on iloperidone’s question able efficacy results versus risperidone.

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Research Update

Placebo response is usually long-lasting

Topics: Antidepressants

Based on data from eight randomized double-blind, placebo-controlled trials, researchers found that 79% of patients who responded to placebo in the initial phase of the trial maintained their response while continuing to take placebo during the continuation phase of the trial.

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Research Update

Intensive early intervention benefits fade after treatment discontinued

An intensive two-year-long early intervention for first episode psychosis showed early promise relative to standard care, yielding superior improvement in both positive and negative symptoms, as well as lower rates of substance abuse and lower antipsychotic medication doses.

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