The Latest on Antidepressants (October)

Date of Issue: 10/01/2009 | Volume: 7 | Number: 10

Issue Links:Learning Objectives | Editorial Information

Teaser to be posted soon.

In This Issue

Article

Which Antidepressant to Choose?

Topics: Antidepressants

There is a strange disconnect between what we psychiatrists do in daily practice and what official antidepressant treatment guidelines recommend. Treatment guidelines typically say, essentially, that all antidepressants are equal in efficacy, but real psychiatrists have strong personal preferences, based on some combination of the scientific literature, the advice of experts, our clinical experience, and perhaps even the personalities of the last drug reps we saw in the office.

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Article

Pristiq: An Update

Topics: Antidepressants

Pristiq (desvenlafaxine extendedrelease tablet) was approved by the FDA in February of 2008 for the treatment of major depression.

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Research Update

Chamomile May Be Effective for GAD

Topics: Anxiety Disorder

Everybody knows that chamomile tea is calming, or at least is supposed to be. But it had never been tested in a placebo controlled study, until now. A recent trial compared chamomile capsules to placebo in the treatment of 57 patients with mild to moderate generalized anxiety disorder.

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Research Update

Long-Term Outcomes of Adolescent Depression Treatment

Topics: Child Psychiatry

The treatment of adolescent depression has stirred much controversy in recent years. Many have raised doubts about the efficacy of both antidepressants and psychotherapy, and whether medications increase the risk of treatment-emergent suicidality is a divisive issue.

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Expert QA

Understanding Antidepressant Research

Topics: Pharmaceutical Industry | Understanding Psychiatric Research

Dr. Turner, recently you and your colleagues published a paper entitled “Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy” (Turner E et al., N Engl J Med 2008;358:252-60). It caused quite a stir in the field. Can you explain your findings?

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