Buprenorphine Treatment

Topics: Addiction Treatment | Buprenorphine | Buprenorphine Induction | Detoxification | Medication for Opioid Use Disorder (MOUD) | Opioid Use Disorder

CATR: Dr. Capurso, given your role as an expert on various things related to addiction and the editor-in-chief of The Carlat Addiction Treatment Report, we’ve had several discussions about buprenorphine treatment. To begin with the basics, why use buprenorphine at all? Dr. Capurso: Buprenorphine binds to the mu-opioid receptor, the very same receptor

Buprenorphine Induction Without Withdrawal

Topics: Buprenorphine | Buprenorphine Induction | medication of opioid use disorder (MOUD) | Opioid Use Disorder

REVIEW OF: Ahmed S et al, Am J Addict 2021;30(4):305–315 Buprenorphine is notorious for precipitating withdrawal in patients who have recently taken opioids. Its high receptor affinity and partial agonism at the mu receptor can make inductions tricky. Giving it too soon can cause severe withdrawal, yet giving it too late means patients are in disco