Cannabidiol for Crack-Cocaine Craving: Negative Findings

Topics: Addiction Treatment | Cannabidiol | Cocaine | craving

Review of: de Meneses-Gaya C et al, Braz J Psychiatry 2020 (Epub ahead of print) Cocaine use disorder is notoriously difficult to treat, with no approved pharmacological treatments. Brazil, where this study was done, is said to have one of the highest cocaine consumption rates in the world (Abdalla RR et al, Addict Behav 2014;39(1):297–301), and us

Amphetamines and Topiramate for Cocaine Use Disorder

Topics: Cocaine | Pharmacology | Research | Research Update

Review of: Levin FR et al, Drug Alcohol Depend 2020;206:107700 In 2017, an estimated 2.2 million Americans used cocaine, with about 966,000 of them meeting criteria for cocaine use disorder (CUD) (SAMHSA, 2018). Unfortunately, there are still no FDA-approved treatments for CUD. Amphetamines increase synaptic dopamine transmission and may therefore re