Ketamine for Depression

Topics: Depressive Disorder | Free Articles

TCPR: Were any other medications given during the infusion in your study? Dr. Mathew: Participants in our study were washed off of any other psychotropic drug, including antidepressants, for at least a  seven-day period prior to infusion. And the reason for that was that we want to look at other biological measures such as neurotrophic factors and

Minimal Benefits, Substantial Side Effects in Treating Depression with Atypical Antipsychotics

Topics: Depressive Disorder | Research Updates

Vortioxetine (Brintellix) approved for MDD

Topics: Depressive Disorder | News of Note

Physical Activity Improves Mental Health in Obese Adults

Topics: Depressive Disorder | Research Updates

Subject: Exercise Short Description: Physical Activity Improves Mental Health in Obese Adults Background: Much research over the past decade has demonstrated the benefits of physical exercise in reducing symptoms of anxiety and depression. What’s not clear, however, is whether exercise provides a benefit specifically in obese adults, or wheth

Transcranial Direct Current Stimulation for Depression

Topics: Depressive Disorder

Subject: Depression Short Description: Transcranial Direct Current Stimulation for Depression Background:  Nonpharmacological methods to treat depression include more than just ECT: recent developments include promising strategies like repetitive transcranial magnetic stimulation (rTMS) and vagal nerve stimulation (VNS). Another procedure, trans

Study Looks at Use of TMS to Treat Depression

Topics: Depressive Disorder | Research Updates

Subject: Depression Short Description: Study Looks at Use of TMS to Treat Depression Background: Transcranial magnetic stimulation, or TMS, was approved by the FDA for treatment of major depression in October 2008. A newly published observational study evaluating the effectiveness of TMS treatment in more than 300 patients at 42 clinical sett

Low Dose Abilify Ineffective as Adjunct for MDD

Topics: Depressive Disorder | Research Updates

Subject: Depression Short Description: Low Dose Abilify Ineffective as Adjunct for MDD Background: Augmentation of antidepressants with antipsychotics has become a common practice, and aripiprazole (Abilify) has been FDA-approved at doses from 2 mg/day to 15 mg/day for this purpose. In a recent report, 225 patients with major depressive disor

Patient Preference Not a Good Predictor of Treatment Response

Topics: Depressive Disorder | Research Updates

Subject: Patient Preference Short Description: Patient Preference Not a Good Predictor of Treatment Response Background: Do patients with major depressive disorder (MDD) respond better when psychiatrists offer the type of treatment—medication or psychotherapy—that the patient prefers? And do patients’ beliefs about what causes their d

Depression

Topics: Depressive Disorder | Research Updates

Subject: DEPRESSION Short Description: Deep Brain Stimulation: A New Somatic Therapy for Depression? Background: Deep brain stimulation (DBS) has suddenly begun popping up in both the medical journals and the mainstream media as a potential treatment for treatment resistant depression. DBS involves the placement of tiny electrodes in the brai

Cognitive Behavioral Therapy Versus Medications for Depression: How Do They Compare?

Topics: Depressive Disorder | Psychotherapy

Medications are more effective than therapy.” “Therapy is just as effective, but lasts longer.” Depending on your biases, you can probably find evidence to support either of the above propositions. Dozens of trials compare cognitive behavior therapy (CBT) to a waiting-list control group, and hundreds of trials examine how antidepressants co

Cognitive Behavioral Therapy Versus Medications for Depression: How Do They Compare? [Free Article]

Topics: Depressive Disorder | Psychotherapy

Deplin: Is it Just Folate by Another Name?

Topics: Depressive Disorder | Natural Medications

Patients are probably asking you about Deplin, or L-methylfolate, a version of folic acid that is being marketed by Pamlab as an adjunctive treatment for depression. In a prior issue of TCPR (June 2009) we reviewed available information on Deplin, concluding that there’s little evidence it is any more helpful for depression than much cheaper folic aci

Genes Plus Environment in Psychiatry: View Positive Studies Skeptically

Topics: Depressive Disorder | Genetics and Psychiatry

Subject: GENETICS Short Description: Genes Plus Environment in Psychiatry: View Positive Studies Skeptically Background: Common sense dictates that genetic predispositions probably interact with life stressors to influence our mental health. Plenty of research has been published to evaluate whether this is actually true, but findings have bee

St. John’s Wort or Celexa for Minor Depression?

Topics: Antidepressants | Depressive Disorder | Natural Medications

Serotonin Transporter Genotype: Involved In Depression After All?

Topics: Depressive Disorder

Combined Antidepressants No More Effective than Monotherapy

Topics: Antidepressants | Depressive Disorder

“Soft” Bipolar Does Not Affect Antidepressant Treatment Outcomes

Topics: Bipolar Disorder | Depressive Disorder

Long-Term Exercise May Extend Remission in Depression

Topics: Antidepressants | Depressive Disorder

Antidepressants Found Ineffective for Subthreshold Depression

Topics: Depressive Disorder

Insomnia and Mood Disorders in Adolescents

Topics: Child Psychiatry | Depressive Disorder

Insomnia and sleep disturbance are common symptoms of depression in adults, but this is not always the case in adolescents. In fact, a group of researchers at the University of Pittsburgh who studied insomnia in depressed teens found that, compared to adults, insomnia in adolescents is different—very different. A 2005 study examined sleep differenc