Melatonin for Sleep-Onset Insomnia

Topics: Dosage Timing | Melatonin | Sleep | Sleep Onset Insomnia

REVIEW OF: Wei S et al, Sleep Medicine 2020;68:1–8 Sleep-onset insomnia, characterized by difficulty falling asleep and daytime fatigue, is a common problem among youth. While sleep hygiene is the first step, families often have trouble implementing such measures, which include regular wake-up times, daily exercise, shutting down screens in the eve

Starting Buprenorphine: Is Timing Everything?

Topics: Buprenorphine | Dosage Timing | Opioid Use Disorder

Review of: Jakubowski A et al, J Subst Abuse Treat 2020;119:108140 Buprenorphine is a safe and effective treatment of opioid use disorder (OUD), but studies show that less than two-thirds of patients treated with buprenorphine are still in treatment 6 months later (Timko C et al, J Addict Dis 2016;35(1):22–35). Since the highest rate of dropout is