Generalized Anxiety Disorder Carlat Reports

Expert Q&A

Treating Anxiety Disorders in Children: The New AACAP Clinical Practice Guideline

From The Carlat Child Psychiatry Report, ADHD in Children and Adolescents

CCPR: Welcome, Dr. Abright. Tell us how the American Academy of Child and Adolescent Psychiatry (AACAP) created the Clinical Practice Guideline on the Assessment and Treatment of Anxiety Disorders in Children and Adolescents (Walter HJ et al, J Am Acad Child Adolesc Psychiatry 2020;59(10):1107–1124).Dr. Abright: The AACAP Committee on Quality Issues (

Expert Q&A

Benzodiazepines: Old Medicines, New Concerns

From The Carlat Addiction Treatment Report, Emerging Risks for Old Medications

CATR: To begin, tell us about the research and clinical work you do. Dr. Morford: I am an assistant professor at the Yale School of Medicine in the Program of Addiction Medicine. I trained as a general internist, and I see patients primarily at a large opioid treatment program and in an inpatient setting on an addiction consult service. I’m involved

Clinical Update

Buspirone: Still Effective After All These Years?

From The Carlat Psychiatry Report, Stopping Psych Meds Part 1

When buspirone was released in 1986, it was advertised as providing “a different kind of calm.” Unfortunately, physicians and their patients weren’t ready to accept the kind of calm that required several weeks to take effect, when punchier, quicker benzos were the standard route to tranquility. Although buspirone is FDA approved for generalized an

Research Update

Rest Easy: Benzos, Z-Drugs, and Dementia

From The Carlat Psychiatry Report, Mind-Gut Connection

Review of: Osler M and Jorgensen MB, Am J Psych 2020;177(6):497–505 Study TYPE: Epidemiologic case-control Few psychotropics stir controversy like the benzodiazepines. While they work well for anxiety and insomnia, their risks of abuse and dependence have always nagged at us. More recently, some research has suggested that long-term use increase

Clinical Update

Silexan: A Novel Anxiolytic

From The Carlat Psychiatry Report, Traumatic Brain Injury

Patients with generalized anxiety disorder (GAD) often look to medications for help, but GAD is one of the disorders where medications are likely to disappoint. Effect sizes tend to fall in the small range (0.2–0.3) with meds for GAD, including SSRIs, SNRIs, buspirone, and pregabalin (Lyrica). Only the benzodiazepines have an effect in GAD that’s bi

Research Update

Pharmacology for GAD: Complex Choices

From The Carlat Psychiatry Report, Adult ADHD

Review of: Slee A et al, Lancet 2019;393(10173):768–777 Study Type: Network meta-analysis With over 2 dozen choices, how do we pick a medication for generalized anxiety disorder (GAD)? The authors of this network meta-analysis sought to answer this question. Network meta-analysis allows researchers to gauge treatments that haven’t been directly c

Ask The Editor

Is Paxil the Best SSRI for Anxiety?

From The Carlat Psychiatry Report, How to Talk about Medication

Dear Dr. Aiken: Your review of Paxil’s risks in the May issue failed to mention a benefit that’s unique to this drug. Isn’t it the best SSRI for anxiety? Dr. Aiken: Paroxetine’s (Paxil’s) reputation as the anti-anxiety SSRI got off to a running start. It was first launched for panic disorder in 1996, two years before its approval for depres