Hypothyroidism and Depression: Just How Related Are They?

Topics: Depression | Medical Comorbidities | Meta-analysis

REVIEW OF: Bode H et al, JAMA Psychiatry 2021;78(12):1375–1383 STUDY TYPE: Meta-analysis of epidemiologic and population-based studies Hypothyroidism and depression are related, right? Actually, the connection is not so clear. Prior studies have supported a connection, but they had limitations, such as small sample sizes, patients with severe di

Antipsychotics for Methamphetamine Psychosis

Topics: Antipsychotic | Meta-analysis | Methamphetamines | Psychosis

REVIEW OF: Srisurapanont M et al, Drug Alcohol Depend 2021;219:108467 STUDY TYPE: Systematic review and network meta-analysis Methamphetamine psychosis (MAP) is difficult to treat, and there are only so many antipsychotics in our repertoire. Randomized clinical trials (RCTs) to manage MAP are few and far between, and the literature thus far has in

Is AA the Toast of the Town?

Topics: Alcohol | Alcohol use disorder | Behavioral treatment | Meta-analysis | Systematic review

Review of: Kelly JF et al, Cochrane Database Syst Rev 2020;(3):CD010216 Alcoholics Anonymous (AA) is the most widely used psychosocial treatment for alcohol use disorder (AUD). Historically, low quality of scientific evidence has limited our ability to speak confidently of AA’s effectiveness. Previous Cochrane reviews (which tend to occupy the high