Drug Overdoses in the US: Trends and Prevention Strategies

Topics: fentanyl | Harm reduction | Naloxone | Opioid epidemic | Opioids

CATR: Welcome, Dr. Sharfstein. Tell us about your background. Dr. Sharfstein: I am professor of the Practice of Health Policy and Management at the Johns Hopkins Bloomberg School of Public Health. I’m a pediatrician by training and have worked in the public sector. I was a health policy advisor for Congressman Henry Waxman and the health commissioner

Naloxone Prescribing

Topics: Harm reduction | Naloxone | Opioid epidemic | Opioid Use Disorder

CATR: Welcome, Dr. Coffin. Tell us what you do. Dr. Coffin: I’m a physician boarded in addiction medicine, infectious disease, and internal medicine. I am the director of substance use research at the San Francisco Department of Public Health, and on faculty at UCSF. My research is mainly in substance use, and I have various projects dealing with tre

A New High-Dose Naloxone: Life Saver or Punishment?

Topics: Harm reduction | Naloxone | Opioid Use Disorder

The FDA approved a new intranasal formulation of naloxone on April 30, 2021. Called KLOXXADO, this formulation distinguishes itself from other delivery systems by its higher dose, with each nasal spray containing 8 mg of naloxone. In comparison, the most widely used naloxone product, Narcan Nasal Spray, contains 4 mg of naloxone. What’s the rationa

New Generic Versions of Naloxone

Topics: Addiction | Addiction Treatment | Clinical practice | Medication | Naloxone | News of Note | Opioid epidemic | Opioid Use Disorder | Opioids | Overdose | Pharmacology

Naloxone, a rescue medication effective for reversing opioid overdoses, will soon be available in two generic forms for layperson use. Naloxone nasal spray is the generic version of branded Narcan Nasal, which currently sells for $150 for two doses. The generic version will be much cheaper. Naloxone auto-injector is the generic version of Evzio au