SSRIs vs SNRIs in Pediatric Anxiety Disorders: Which Are More Tolerable?

Topics: Anxiety | efficacy | Obsessive Compulsive Disorder | OCD | Serotonin Norepinephine Reuptake Inhibitors | Serotonin Specific Reuptake Inhibitors | Side Effects | SNRIs | SSRIs

REVIEW OF: Mills JA and Strawn JR, J Am Acad Child Adolesc Psychiatry 2020;59(11):1240–1251 STUDY Type: Meta-analysis For children with anxiety disorders and OCD, SSRIs produce faster and greater improvement than SNRIs (Strawn JR et al, J Am Acad Child Adolesc Psychiatry 2018;57(4):235–244.e2). Unfortunately, adverse effects slow down our dose

Long-Term Treatment Response in Pediatric OCD

Topics: Cognitive Behavioral Therapy | Obsessive Compulsive Disorder | Serotonin Specific Reuptake Inhibitors

REVIEW OF: Melin K et al, J Am Acad Child Adolesc Psychiatry 2020;59(2):244–253 OCD affects 1%–4% of children and adolescents and can be chronically debilitating in 40%–60% of cases. The well-known Pediatric OCD Treatment Study (POTS) published in 2004 showed that CBT and sertraline had comparable benefits over 12 weeks of treatment; however

Quetiapine in Bipolar With OCD

Topics: Antipsychotics | Bipolar Disorder | Co-occurring disorders | Obsessive Compulsive Disorder | OCD | Quetiapine

REVIEW OF: Sahraian A et al, CNS Spectr 2021;1–5 TYPE OF STUDY: Randomized, double-blind, placebo-controlled clinical trial SSRIs are first-line meds for obsessive-compulsive disorder (OCD), but they may pose risks of mania and rapid cycling when the patient also has bipolar disorder (BD). These conditions overlap more often than expected by chance,

The Schizophrenia-OCD Overlap

Topics: Antipsychotics | Aripiprazole | Clozapine | Comorbidity | Diagnosis | Lamictal | Lamotrigine | Obsessive Compulsive Disorder | OCD | olanzapine | Pharmacology Tips | polypharmacy | Quetiapine | Risperidone | Schizoaffective disorder | Schizophrenia

TCPR: What is schizo-obsessive disorder?Dr. Poyurovsky: Schizo-obsessive disorder (schizo-OCD) is not a DSM diagnosis. The term is used to refer to patients with schizophrenic disorders that have comorbid features of OCD. We see these obsessive-compulsive symptoms in schizophrenia more often than would be expected by chance. About one in four patients h