Treatment-Resistant Depression

Ask The Editor

Wellbutrin Augmentation: When Does It Work?

Topics: Depression | Treatment-Resistant Depression | Wellbutrin

Each month, Editor-in-Chief Chris Aiken, MD, gives advice on a different practice challenge. Dear Dr. Aiken: In the July/August 2018 issue, you wrote that ­bupropion (Wellbutrin) augmentation does not work in ­treatment-resistant depression (TRD). So why do we see it work so often in practice? Dr. Aiken: When all of the studies are averaged tog

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