For decades, the principal treatment for substance use disorders has been psychological therapies. Twelve-step facilitation therapy, modeled after Alcoholics Anonymous, and motivational enhancement therapy are currently the two most widely used. Although disulfiram (Antabuse) hit the U.S. market in 1951, addiction pharmacotherapy was underwhelming for many years. Methadone (Dolophine) eventually arrived in the 1960s to […]

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