Do Antidepressants Cause Switching?
The Carlat Psychiatry Report, Volume 4, Number 8, August 2006
https://www.thecarlatreport.com/newsletter-issue/tcprv4n8/
Issue Links: Learning Objectives | Editorial Information
Topics: Antidepressants
The latest foray into the controversial issue of antidepressant-induced switching appeared in the February issue of The American Journal of Psychiatry (2006;163:232-239). The last time TCPR took up this topic (June 2005), we reviewed a meta-analysis of antidepressant use in bipolar disorder. That paper concluded that SSRIs cause the same rate of manic switching as placebo (Am J Psychiatry 2004;161:1537-1547). The authors of the newly published research would beg to differ.
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Daniel Carlat, MD
Editor-in-Chief, Publisher, The Carlat Report.
Dr. Carlat has disclosed that he has no relevant relationships or financial interests in any commercial company pertaining to this educational activity.