Vagus Nerve Stimulation: A Brief Update
The Carlat Psychiatry Report, Volume 6, Number 1, January 2008
https://www.thecarlatreport.com/newsletter-issue/tcprv6n1/
Issue Links: Learning Objectives | Editorial Information
Topics: Brain Devices | Depressive Disorder
Daniel Carlat, MD
VNS (vagus nerve stimulation) was initially developed and approved for treatment-refractory epilepsy. Cyberonics conducted one sham-controlled study for treatment-resistant depression, and while this double-blind study showed no statistical benefit over placebo, an open-label extension showed enough benefit to impress someone at the FDA.
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Daniel Carlat, MD
Editor-in-Chief, Publisher, The Carlat Report.
Dr. Carlat has disclosed that he has no relevant relationships or financial interests in any commercial company pertaining to this educational activity.