Clozapine for Conduct Disorder in Schizophrenia

Topics: Clozapine | Conduct Disorder | Schizophrenia | Violence

REVIEW OF: Krakowski M et al, Am J Psychiatry 2021;178(3):266–274 STUDY TYPE: Randomized controlled trial We often struggle to find effective interventions for aggressive behavior in patients with schizophrenia. For patients with a history of conduct disorder, the task is even more challenging. Patients with schizophrenia will often have shown s

Heart Rate Changes Linked to ­Emotional Dysregulation

Topics: ADHD | Anxiety | attention | Conduct Disorder | Depression | Dysregulation | Emotional dysregulation | Heart rate

Review of: Deutz MH et al, J Am Acad Adolesc Psychiatry 2019;58(6):589–599 Can we use heart rate to assess and track psychopathology? Child psychiatrists associate lower resting heart rate (HR-rest) and heart rate reactivity (HR-reactivity) with externalizing behaviors such as disruptive behaviors and aggression (“under-arousal”) and elevations