Can We Treat Depression by Targeting Inflammation?

Topics: Antibiotic | Depression | Inflammation | Minocycline | Mood | Pharmacotherapy

REVIEW OF: Zazula R et al, Aust N Z J Psychiatry 2021;55(8):784–798 Recent data suggest inflammation may play a role in depression, prompting research into the efficacy of minocycline—a tetracycline antibiotic with anti-inflammatory effects—as an augmentation agent in the treatment of major depressive disorder (MDD). This study was a pooled