Sex-Based Treatment of Schizophrenia

Topics: Estrogen | Female Issues in Psychiatry | Gender | Hormone Replacement Therapy | HRT | Oral Contraceptives | Osteporosis | Post-menopausal | Prolactin | Raloxifene | SERM (Selective Estrogen Receptor Modulator) | Women’s Issues in Psychiatry

CHPR: Dr. Kulkarni, you’ve written about sex-based differences in symptoms and prognosis of schizophrenia. What are some of these differences? Dr. Kulkarni: Compared to men, women with schizophrenia experience a more benign course of illness, including fewer psychiatric relapses and hospitalizations. They are more likely to be employed and married an

Oral Contraceptive Users and Depressive Symptoms

Topics: adolescents | Depression | Oral Contraceptives | teens

Review of: de Wit AE et al, JAMA Psychiatry 2019;77(1):52–59 Since the dawn of their widespread use in the 1960s, we’ve worried about the impact of oral contraceptives (OCP) on mood. But the research to date has been inconsistent, with studies reporting negative, positive, or no effects on mood. Heterogeneity in study population and design may un

Mood and Menopause

Topics: Antidepressants | Citalopram | Depressive Disorder | Effexor | Escitalopram | Female Issues in Psychiatry | Fluoxetine | gabapentin | Gender | Hormone Replacement Therapy | Oral Contraceptives | Prozac | Serotonin Specific Reuptake Inhibitors (SSRIs) | SSRIs | Women’s Issues in Psychiatry

TCPR: When does perimenopausal depression tend to start?Dr. Nonacs: It’s during the transition into menopause that women are most vulnerable to depression. And that transition can actually take quite a while, like 5–7 years. TCPR: How does it present?Dr. Nonacs: Often they’ve had a history of depression, but have done fairly well up to this point